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(iv) Another explanation is that nOexposure may produce morphological alterations in therespiratory tract, especially in the centriacinar region, wherethe conducting and gas exchange airways meet.

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Orally administeredatropinic drugs are bronchodilators, but lesseffective than adrenergic drugs; not clinically used.They dry up secretion in the respiratory tract,may lead to its inspissation and plugging ofbronchioles resulting in alveolar collapse andpredisposition to infection.

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